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In biochemical assays, C1-27 had the highest affinity for GSTO1, which is supported by the structure in that C1-27 makes more interactions with the protein than the other two inhibitors

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In addition, increasing STAT3 from activated JAK/STAT signaling pathway might be involved in the apoptosis of cell through PTEN, which inhibits Akt cascade, resulting in exacerbated hyperglycemia 136 (Fig

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ZitkaOSkalickovaSGumulecJMasarikMAdamVHubalekJet alRedox status expressed as GSH:GSSG ratio as a marker for oxidative stress in paediatric tumour patients